September 25, 2017 |
Reducing Hypersensitivity to Pain in Fibromyalgia Patients
July 30, 2014  | 

Gainesville, FL — Patients diagnosed with fibromyalgia complain of chronic pain throughout their bodies, but often doctors have difficulty detecting what causes the pain, and therefore, how to treat it.

These patients also complain of hyperalgesia, or increased sensitivity to pain. A University of Florida study published in the July issue of the European Journal of Pain has found that injections of the painkiller lidocaine in peripheral tissues such as muscles in the shoulders or buttocks reduced hyperalgesia, bringing researchers one step closer to understanding how chronic pain works within these patients.

“We hypothesized that if pain comes from the peripheral tissues, and we can take this pain away by injecting local anesthetics, then this would be indirect proof of the importance of peripheral tissues for the clinical pain of these individuals,” said Roland Staud, M.D., a professor of medicine within the UF College of Medicine’s department of medicine.

Sixty-two women diagnosed with fibromyalgia were involved in the study. Each woman received two injections in the trapezius muscles of the shoulders and the gluteal muscles of the buttocks, for a total of four injections per patient. The women were divided into several groups and given mechanical and heat pain stimuli immediately before and then 30 minutes after the injections. One group received four saline injections. The second group received four lidocaine injections. Continue>

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