Chemical Compound Decreases Effects of Multiple Sclerosis
Riverside, CA – Given the debilitating effects of Multiple sclerosis (MS), an aggressive search is on among scientists to find a cure. Currently available therapies are only partially effective, however, in preventing the onset of permanent disability in MS patients. What would be immensely helpful is a drug that could minimize the degeneration of axons, thus reducing the rate and degree of MS progression. Better still would be if this drug could stimulate “remyelination,” the re-sheathing of the axons, restoring fast and uninterrupted flow of nerve impulses.
“This drug, which we administered on transgenic mice, can potentially halt the symptoms and reverse ongoing motor deficit due to MS,” said Seema K. Tiwari-Woodruff, an associate professor in the UC Riverside School of Medicine whose lab led the study. “Our study shows that Ind-Cl can remyelinate axons which have gotten injured not just in MS but also traumatic brain injury and spinal cord injury.” Continue>
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